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1

Bioactive natural products derived from the Central African flora against neglected tropical diseases and HIV

Zofou, Denis, Ntie-Kang, Fidele, Sippl, Wolfgang, Efange, Simon M. N.

Journal:

Natural Product Reports

Year:

2013

Language:

english

File:

PDF, 2.47 MB

english, 2013

2

Selective Visualization of Rodent Locus Ceruleus by a Radiolabeled N-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Analog

S. M. N. Efange, D. Mash, F. Hefti, H. F. Kung, J. Billings

Journal:

Journal of Neurochemistry

Year:

1989

Language:

english

File:

PDF, 1.92 MB

english, 1989

3

Assessing the pharmacokinetic profile of the CamMedNP natural products database: anin silicoapproach

Ntie-Kang, Fidele, Mbah, James A, Lifongo, Lydia L, Owono Owono, Luc C, Megnassan, Eugene, Meva'a Mbaze, Luc, Judson, Philip N, Sippl, Wolfgang, Efange, Simon MN

Journal:

Organic and Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 461 KB

english, 2013

4

1-Aryl-1,2,3,4-tetrahydroisoquinolines as potential antimalarials: synthesis, in vitro antiplasmodial activity and in silico pharmacokinetics evaluation

Hanna, Joelle Ngo, Ntie-Kang, Fidele, Kaiser, Marcel, Brun, Reto, Efange, Simon M. N.

Journal:

Year:

2014

Language:

english

File:

PDF, 532 KB

english, 2014

5

Isolation and characterization of filaricidal compounds from the stem bark of Voacanga africana, a plant used in the traditional treatment of onchocerciasis in Cameroon

Smith, Babiaka Borakaeyabe, James, Ajeck Mbah, Fidelis, Cho Ngwa, Jonathan, Alunge Metuge, Simon, Mbua Ngale Efange

Journal:

Journal of Medicinal Plants Research

Year:

2015

Language:

english

File:

PDF, 177 KB

english, 2015

6

In vitro and in vivo studies on anti-malarial activity of Commiphora africana and Dichrostachys cinerea used by the Maasai in Arusha region, Tanzania

Kweyamba, Prisca A., Zofou, Denis, Efange, Noella, Assob, Jules-Clement N., Kitau, Jovin, Nyindo, Mramba

Journal:

Malaria Journal

Year:

2019

Language:

english

File:

PDF, 917 KB

english, 2019

7

Imaging of cholinergic terminals using the radiotracer [18F](+)-4-fluorobenzyltrozamicol: In vitro binding studies and positron emission tomography studies in nonhuman primates

Robert H. Mach, Mary Lou Voytko, Richard L.E. Ehrenkaufer, Michael A. Nader, Joseph R. Tobin, Simon M.N. Efange, Stanley M. Parsons, H. Donald Gage, Cynthia R. Smith, Thomas E. Morton

Journal:

Year:

1997

Language:

english

File:

PDF, 144 KB

english, 1997

8

Cholinergic activity of aged rhesus monkeys revealed by positron emission tomography

Mary Lou Voytko, Robert H. Mach, H. Donald Gage, Richard L.E. Ehrenkaufer, Simon M.N. Efange, Joseph R. Tobin

Journal:

Year:

2001

Language:

english

File:

PDF, 68 KB

english, 2001

9

ChemInform Abstract: Modified Ibogaine Fragments: Synthesis and Preliminary Pharmacological Characterization of 3-Ethyl-5-phenyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]benzothiophenes.

Simon M. N. Efange, Deborah C. Mash, Anil B. Khare, Quinjie Ouyang

Journal:

Year:

1999

File:

PDF, 32 KB

1999

10

Natural Products: A Continuing Source of Inspiration for the Medicinal Chemist

S. Mbua Ngale Efange

Journal:

Year:

2003

File:

PDF, 53 KB

2003

11

p-[18F]fluorobenzyltrozamicol ([18F]FBT): Molecular decomposition-reconstitution approach to vesamicol receptor radioligands for positron emission tomography

S.M.N. Efange, R.H. Mach, A. Khare, R.H. Michelson, P.A. Nowak, P.H. Evora

Journal:

Applied Radiation and Isotopes

Year:

1994

Language:

english

File:

PDF, 698 KB

english, 1994

12

Ibogaine analogues. Synthesis and preliminary pharmacological evaluation of 7-heteroaryl-2-azabicyclo[2.2.2]oct-7-enes

Daniele Passarella, Raffaele Favia, Alessandra Giardini, Giordano Lesma, Marisa Martinelli, Alessandra Silvani, Bruno Danieli, Simon M.N Efange, Deborah C Mash

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 228 KB

english, 2003

13

Oxidation Products Arising from the Action of Monoamine Oxidase B on 1-Methyl-4-Benzyl-1,2,3,6-Tetrahydropyridine, a Nonneurotoxic Analogue of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine

Sergey O. Sablin, Matthew J. Krueger, Sergey O. Bachurin, Lev S. Solyakov, Simon M. N. Efange, Thomas P. Singer

Journal:

Journal of Neurochemistry

Year:

1994

Language:

english

File:

PDF, 485 KB

english, 1994

14

Pargyline-Sensitive selective accumulation of a radiolabeled MPTP analog in the primate cerebral cortex and basal ganglia

S. M. N. Efange, H. F. Kung, D. C. Mash, M. Jabir, J. Billings, J. Pablo, A. Dutta, A. Freshler

Journal:

Year:

1990

Language:

english

File:

PDF, 759 KB

english, 1990

15

Molecular determinants in the bioactivation of the dopaminergic neurotoxinN-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

S. M. N. Efange, R. J. Boudreau

Journal:

Journal of Computer-Aided Molecular Design

Year:

1991

Language:

english

File:

PDF, 1.69 MB

english, 1991

16

A break of public key cryptosystem PKCY

Maozhi Xu, Efang Wang

Journal:

Science China Technological Sciences

Year:

1997

Language:

english

File:

PDF, 331 KB

english, 1997

17

Empirical Likelihood Confidence Region for Parameters in Semi-linear Errors-in-Variables Models

HENGJIAN CUI, EFANG KONG

Journal:

Scandinavian Journal of Statistics

Year:

2006

Language:

english

File:

PDF, 625 KB

english, 2006

18

Characterization and Distribution of Transferrin Receptors in the Rat Brain

Deborah C. Mash, John Pablo, Donna D. Flynn, Simon M. N. Efange, William J. Weiner

Journal:

Journal of Neurochemistry

Year:

1990

Language:

english

File:

PDF, 2.02 MB

english, 1990

19

Synthesis and biological activities of 2-pyrimidinone nucleosides. 2. 5-Halo-2-pyrimidinone 2'-deoxyribosides

Efange, Simon M. N., Alessi, Elaine M., Shih, H. C., Cheng, Yung Chi, Bardos, Thomas J.

Journal:

Journal of Medicinal Chemistry

Year:

1985

Language:

english

File:

PDF, 1.05 MB

english, 1985

20

Molecular size and flexibility as determinants of selectivity in the oxidation of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs by monoamine oxidase A and B

Efange, S. M. N., Michelson, R. H., Tan, A. K., Krueger, M. J., Singer, T. P.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 908 KB

english, 1993

21

Chromaproline and Chromaperidine, nicotine agonists, and Donepezil, cholinesterase inhibitor, enhance performance of memory tasks in ovariectomized rats

V.N Luine, G Mohan, Z Tu, S.M.N Efange

Journal:

Pharmacology Biochemistry and Behavior

Year:

2002

Language:

english

File:

PDF, 286 KB

english, 2002

22

Lipophilic amino alcohols with calcium channel blocking activity

Anil S. Sipahimalani, John L. Werth, Robert H. Michelson, Aloke K. Dutta, S.Mbua N. Efange, Stanley A. Thayer

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 996 KB

english, 1992

23

Vesamicol analogues as sigma ligands: Molecular determinants of selectivity at the vesamicol receptor

Simon M.N. Efange, Robert H. Mach, Cynthia R. Smith, Anil B. Khare, Catherine Foulon, Surya K. Akella, Steven R. Childers, Stanley M. Parsons

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 766 KB

english, 1995

24

Potential environmental neurotoxins related to 1-methyl-4-phenylpyridinium: Selective toxicity of 1-methyl-4-(4′-acetamidophenyl)-pyridinium and 1-methyl-4-cyclohexylpyridinium for dopaminergic neurons in culture

Patrick P. Michel, Bhuvaneshari K. Dandapani, Simon M.N. Efange, Franz Hefti

Journal:

Experimental Neurology

Year:

1990

Language:

english

File:

PDF, 2.70 MB

english, 1990

25

The vesamicol receptor ligand (+)-meta-[1251]iodobenzyltrozamicol {(+)-[125¦]-MIBT} reveals blunting of the striatal cholinergic response to dopamine D2 receptor blockade in the 6-hydroxydopamine (6-OHDA)-lesioned rat: Possible implications for parkinson's disease

Simon M.N. Efange, Rosemary B. Langason, Anil B. Khare, Walter C. Low

Journal:

Year:

1996

Language:

english

File:

PDF, 666 KB

english, 1996

26

Comparative tissue distribution of conformationally restricted radioiodinated vesamicol receptor ligands

S.M.N. Efange, A.B. Khare, R.B. Langason

Journal:

Nuclear Medicine and Biology

Year:

1995

Language:

english

File:

PDF, 745 KB

english, 1995

27

In vitro anti-Helicobacter pylori activity of extracts of selected medicinal plants from North West Cameroon

Roland N. Ndip, Alertia E. Malange Tarkang, Susan M. Mbullah, Henry N. Luma, Agnes Malongue, Lucy M. Ndip, Kennedy Nyongbela, Clare Wirmum, Simon M.N. Efange

Journal:

Journal of Ethnopharmacology

Year:

2007

Language:

english

File:

PDF, 138 KB

english, 2007

28

Vesicular Acetylcholine Transporter Density and Alzheimer’s Disease

S.M.N Efange, E.M Garland, J.K Staley, A.B Khare, D.C Mash

Journal:

Neurobiology of Aging

Year:

1997

Language:

english

File:

PDF, 150 KB

english, 1997

29

Morphine-induced spinal cholinergic activation: in vivo imaging with positron emission tomography

H.Donald Gage, Jennifer C Gage, Joseph R Tobin, Astrid Chiari, Chuanyao Tong, Ze-Min Xu, Robert H Mach, Simon M.N Efange, Richard L.E Ehrenkaufer, James C Eisenach

Journal:

Year:

2001

Language:

english

File:

PDF, 103 KB

english, 2001

30

Synthesis and biological characterization of stable and radioiodinated (±)-trans-2-hydroxy-3-P{4-(3-iodophenyl)piperidyl}-1,2,3,4-tetrahydronaphthalene (3′-IBVM)

S.M.N Efange, K von Hohenberg, A.B Khare, Z Tu, R.H Mach, Stanley M Parsons

Journal:

Nuclear Medicine and Biology

Year:

2000

Language:

english

File:

PDF, 530 KB

english, 2000

31

Measurement of functional cholinergic innervation in rat heart with a novel vesamicol receptor ligand

Paul R. Coffeen, S.M.N. Efange, George C. Haidet, Scott McKnite, Rosemary B. Langason, A.B. Khare, Jennifer Pennington, Keith G. Lurie

Journal:

Nuclear Medicine and Biology

Year:

1996

Language:

english

File:

PDF, 585 KB

english, 1996

32

(+)-p-([18F]fluorobenzyl)spirotrozamicol {(+)-[18F]Spiro-FBT}: synthesis and biological evaluation of a high-affinity ligand for the vesicular acetylcholine transporter (VAChT)

S.M.N Efange, M.A Nader, R.L.E Ehrenkaufer, A.B Khare, C.R Smith, T.E Morton, R.H Mach

Journal:

Nuclear Medicine and Biology

Year:

1999

Language:

english

File:

PDF, 273 KB

english, 1999

33

N-(3-iodophenyl)trozamicol (IPHT) and related inhibitors of vesicular acetylcholine transport: synthesis and preliminary biological characterization

A.B Khare, R.B Langason, S.M Parsons, R.H Mach, S.M.N Efange

Journal:

Nuclear Medicine and Biology

Year:

1999

Language:

english

File:

PDF, 399 KB

english, 1999

34

Synthesis and in Vitro and in Vivo Evaluation of 18 F-Labeled Positron Emission Tomography (PET) Ligands for Imaging the Vesicular Acetylcholine Transporter

Tu, Zhude, Efange, Simon M. N., Xu, Jinbin, Li, Shihong, Jones, Lynne A., Parsons, Stanley M., Mach, Robert H.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 640 KB

english, 2009

35

Pharmacological characterization of the vesamicol analogue (+)-[125I]MIBT in primate brain

Julie K Staley, Deborah C Mash, Stanley M Parsons, Anil B Khare, Simon M.N Efange

Journal:

European Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 299 KB

english, 1997

36

Bioassay-guided discovery of antibacterial agents: in vitro screening of Peperomia vulcanica, Peperomia fernandopoioana and Scleria striatinux

James A Mbah, Moses N Ngemenya, Ashime Louis Abawah, Smith B Babiaka, Lina N Nubed, Kennedy D Nyongbela, Njimoh Dieudonne Lemuh, Simon MN Efange

Journal:

Annals of Clinical Microbiology and Antimicrobials

Year:

2012

Language:

english

File:

PDF, 342 KB

english, 2012

37

[Advances in Phytomedicine] Ethnomedicine and Drug Discovery Volume 1 || Chapter 5 Natural products: a continuing source of inspiration for the medicinal chemist

Efange, S Mbua Ngale

Year:

2002

Language:

english

File:

PDF, 452 KB

english, 2002

38

A SINGLE-INDEX QUANTILE REGRESSION MODEL AND ITS ESTIMATION

Kong, Efang, Xia, Yingcun

Journal:

Econometric Theory

Year:

2012

Language:

english

File:

PDF, 469 KB

english, 2012

39

Okundoperoxide, a Bicyclic Cyclofarnesylsesquiterpene Endoperoxide from Scleria striatinux with Antiplasmodial Activity

Efange, Simon M. N., Brun, Reto, Wittlin, Sergio, Connolly, Joseph D., Hoye, Thomas R., McAkam, Thomas, Makolo, Felix L., Mbah, James A., Nelson, Dorian P., Nyongbela, Kennedy D., Wirmum, Clare K.

Journal:

Journal of Natural Products

Year:

2009

Language:

english

File:

PDF, 85 KB

english, 2009

40

Flexible N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analog: synthesis and monoamine oxidase catalyzed bioactivation

Efange, S. Mbera Ngale, Michelson, R. H., Remmel, R. P., Boudreau, R. J., Dutta, A. K., Freshler, A.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 819 KB

english, 1990

41

In silicodrug metabolism and pharmacokinetic profiles of natural products from medicinal plants in the Congo basin

Ntie-Kang, Fidele, Lifongo, Lydia L, Mbah, James A, Owono Owono, Luc C, Megnassan, Eugene, Mbaze, Luc, Judson, Philip N, Sippl, Wolfgang, Efange, Simon M N

Journal:

In Silico Pharmacology

Year:

2013

Language:

english

File:

PDF, 503 KB

english, 2013

42

Radioiodinated 2-hydroxy-3-(4-iodophenyl)-1-(4-phenylpiperidinyl)propane: Potential radiotracer for mapping central cholinergic innervation in vivo

Efange, S.M.N., Dutta, A.K., Michelson, R.H., Kung, H.F., Thomas, J.R., Billings, J., Boudreau, R.J.

Journal:

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology

Year:

1992

Language:

english

File:

PDF, 2.14 MB

english, 1992

43

Isolation and identification of an antiparasitic triterpenoid estersaponin from the stem bark of Pittosporum mannii (Pittosporaceae)

Nyongbela, Kennedy D, Lannang, Alain M, Ayimele, Godfred A, Ngemenya, Moses N, Bickle, Quentin, Efange, Simon

Journal:

Asian Pacific Journal of Tropical Disease

Year:

2013

Language:

english

File:

PDF, 304 KB

english, 2013

44

Synthesis and biological evaluation of radioiodinated N-2-(4-piperidyl)ethyl benzamides

Efange, S.M.N., Michelson, R.H., Knusel, B., Hefti, F., Boudreau, R.J., Thomas, J.R., Tennison, J.R.

Journal:

Nuclear Medicine and Biology

Year:

1993

Language:

english

File:

PDF, 2.76 MB

english, 1993

45

Variable Selection for the Single-Index Model

Efang Kong and Yingcun Xia

Journal:

Year:

2007

Language:

english

File:

PDF, 1.20 MB

english, 2007

46

In vivo imaging of the vesicular acetylcholine transporter and the vesicular monoamine transporter

EFANGE, S. M. N.

Journal:

The FASEB Journal

Year:

2000

Language:

english

File:

PDF, 289 KB

english, 2000

47

2-(2-Piperidyl)- and 2-(2-Pyrrolidyl)chromans as Nicotine Agonists: Synthesis and Preliminary Pharmacological Characterization

Efange, Simon M. N., Tu, Zhude, von Hohenberg, Krystyna, Francesconi, Lynn, Howell, Robertha C., Rampersad, Marilyn V., Todaro, Louis J., Papke, Roger L., Kung, Mei-Ping

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 151 KB

english, 2001

48

Synthesis and biodistribution of 99mTc-labeled piperidinyl bis(aminoethanethiol) complexes: potential brain perfusion imaging agents for single photon emission computed tomography

Efange, S. M. N., Kung, Hank F., Billings, J. J., Blau, M.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 735 KB

english, 1988

49

Synthesis and tissue distribution of iodine-125-labeled (m-[125I]iodobenzyl)trozamicol ([125I]MIBT): potential radioligand for mapping central cholinergic innervation

Efange, S. M. N., Michelson, R. H., Khare, A. B., Thomas, J. R.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 2.19 MB

english, 1993

50

Nature-inspired indolyl-2-azabicyclo[2.2.2]oct-7-ene derivatives as promising agents for the attenuation of withdrawal symptoms: synthesis of 20-desethyl-20-hydroxymethyl-11-demethoxyibogaine

Passarella, D., Barilli, A., Efange, S. M. N., Elisabetsky, E., Leal, M. B., Lesma, G., Linck, V. M., Mash, D. C., Martinelli, M., Peretto, I., Silvani, A., Danieli, B.

Journal:

Natural Product Research

Year:

2006

Language:

english

File:

PDF, 144 KB

english, 2006

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